Vidalista 5, which contains 5 mg of Tadalafil, is used to treat erectile dysfunction and sometimes benign prostatic hyperplasia. It is generally safe to take Vidalista 5 mg with antacids, but certain types may reduce its effectiveness. Specifically, antacids that contain aluminum or magnesium hydroxide can potentially affect the absorption of Tadalafil in the body. While the interaction is not typically severe, it is advisable to avoid taking them at the exact same time. A gap of at least 1–2 hours between taking Vidalista 5 and an antacid is usually recommended. Always consult a healthcare provider before combining medications for safety.