Vilitra 10 (which contains Vardenafil, another PDE5 inhibitor like Tadalafil) has a moderate duration of action in the body. Here’s a detailed explanation: Duration and Effects Onset of Action Vilitra 10 usually starts working within 30–60 minutes after oral intake. ****** stimulation is required for an erection; it does not work automatically. How Long It Lasts The effects typically last 4–6 hours, which is shorter than Tadalafil-based drugs like Vidalista (up to 36 hours). Blood levels of Vardenafil decrease gradually over several hours, but the window for effective Vilitra 10 response is generally up to 6 hours. Factors Affecting Duration Food: High-fat meals may delay absorption, slightly reducing effectiveness. Age and Health: Older men or those with liver/kidney issues may metabolize the drug more slowly, prolonging its effects. Alcohol and Lifestyle: Excessive alcohol can reduce both effectiveness and duration. Summary Vilitra 10 is effective for a few hours—usually 4–6 hours after taking it. Unlike Tadalafil-based drugs, it does not provide a full-day or weekend-long window. If you want, I can make a quick comparison of Vilitra 10 vs Vidalista 20/40 in terms of onset and duration, which helps decide which is better for your needs.