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Tadalista 20 mg is a generic medication containing tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor. It is commonly prescribed to treat erectile dysfunction (ED) in men by enhancing blood flow to the penis during sexual arousal, facilitating the achievement and maintenance of an erection. Tadalafil works by inhibiting the PDE5 enzyme, which regulates blood flow in the penis. By blocking this enzyme, tadalafil increases levels of cyclic guanosine monophosphate (cGMP), leading to the relaxation of smooth muscles and dilation of blood vessels in the penis. This process allows increased blood flow, resulting in an erection when sexually stimulated.